An overview of the issues of retinoblastoma in medical research

Therapeutic misconception therapeutic misconception is a term used in research ethics to describe situations where participants believe they are going to receive therapy and do not recognize that they are enrolled in a clinical study (lidz and appelbaum, 2002. Retinoblastoma is an eye cancer that typically develops in children before 5 years of age this cancer develops in the retina—the part of the eye that helps a person see color and light retinoblastoma may affect one or both eyes in about two-thirds of all cases only one eye is affected. An accurate analysis of the currently available literature on both retinoblastoma and epigenetics, coupled with the knowledge of the variegated phenotypic expression of the disease, can easily lead to the conclusion that retinoblastoma is an epigenetic, rather than a genetic disease.

Retinoblastoma is a rare eye cancer affecting about 300 children each year the disease occurs most often in children under the age of 4 years, with 80% of cases occurring under age 3 years and virtually none above age 6 years. Retinoblastoma is a disease in which malignant (cancer) cells form in the tissues of the retina the retina is the nerve tissue that lines the inside of the back of the eye. Summary patient care dr anderson treats a range of pediatric ophthalmology issues, including pediatric cataracts, glaucoma, retinoblastoma and retinopathy of prematurity.

Retinoblastoma treatment market: overview retinoblastoma treatment market is witnessing significant changes due to increasing opportunity for the pharmaceutical and medical devices companies to gain larger untapped market in developing and under developed economies. We would like to show you a description here but the site won't allow us. During and after treatment for retinoblastoma, the main concerns for most families are the short- and long-term effects of the cancer and its treatment, and concerns about the cancer still being there or coming back it's certainly normal to want to put the tumor and its treatment behind you and.

Retinoblastoma is the most common intraocular malignancy in children the unilateral, nonhereditary form of the disease is diagnosed at an average age of approximately 2 years because intraocular disease is usually advanced at diagnosis, patients usually undergo enucleation 1 the bilateral, hereditary form of retinoblastoma is typically diagnosed before 1 year of age when there is hope of. Retinoblastoma (rb) is a rare form of cancer that rapidly develops from the immature cells of a retina, the light-detecting tissue of the eye it is the most common primary malignant intraocular cancer in children, and it is almost exclusively found in young children. The most common eye cancer in children is retinoblastoma, which starts in the cells of the retina cancer can also spread to the eye from other parts of the body treatment for eye cancer varies by the type and by how advanced it is. This section presents information about some of the possible medical professionals that might be involved with retinoblastoma ask your doctor to recommend what other types of doctors, physicians, medical specialists, or other medical professionals should be part of the team for your medical issues.

An overview of the issues of retinoblastoma in medical research

Retinoblastoma is hereditary in all children with cancer in both eyes and in 15% of children with cancer in one eye retinoblastoma does not usually spread beyond the eye, but it occasionally spreads to the brain along the optic nerve (the nerve that leads from the eye to the brain. The research was funded by the national institutes of health, the canadian institutes of health research, the canadian retinoblastoma society, hyland foundation, toronto netralaya and doctors. Consulting with a medical malpractice attorney can help families make peace with the situation by ensuring they have done all they can to further protect their child and other children from issues stemming from a pediatric retinoblastoma diagnosis. Purpose of review: this review highlights many of the most important articles published from june 2007 to may 2008 on retinoblastoma significant advances in molecular biology, translational research, and clinical reports are detailed.

  • An overview of the issues of retinoblastoma in medical research introduction to retinoblastoma as a medical condition including symptoms, diagnosis, misdiagnosis, treatment, prevention, and prognosis.
  • Retinoblastoma is a very rare childhood cancer that forms in the tissues of the retina it can occur in one or both eyes most cases of retinoblastoma are not inherited, but some are, and children with a family history of the disease should have their eyes checked beginning at an early age.
  • The retinoblastoma gene (rb-1) was originally identified as the gene involved in hereditary retinoblastoma however, rb-1 mutations are found in a number of common mesenchymal and epithelial malignancies the retinoblastoma protein (prb) acts as a transcriptional regulator of genes involved in dna.

Abstract = purpose: to provide an overview of the current clinical management of retinoblastoma by discussing the trends in the categorization, treatment, and recent advances in molecular diagnostics as well as therapy for retinoblastoma. Treatment for retinoblastoma in children has two main goals: to prevent the return of the cancer and to preserve vision several types of therapies are used for retinoblastoma, and 99% of children can be cured. The most widely held concept of histogenesis of retinoblastoma holds that it generally arises from a multipotential precursor cell (mutation in the long arm of chromosome 13 band 13q14) that could develop into almost any type of inner or outer retinal cell.

An overview of the issues of retinoblastoma in medical research
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